Dr. Sudha Seshadri, MD, a behavioral neurologist and neuroepidemiologist, is Director of the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases and the Robert R. Barker Distinguished University Professor of Neurology, Psychiatry and Cellular and Integrative Physiology at the Joe and Teresa Long School of Medicine at University of Texas Health Sciences Center, San Antonio, TX. Here, she combines patient care for neurodegenerative and vascular brain disorders with clinical trials, biological and computational research, population neuroscience, public health, mentoring, education and advocacy with a focus on Hispanic health.
She holds adjunct Professor appointments in the Department of Neurology at the Boston University School of Medicine, Boston, MA and at the University of Texas School of Public Health at Houston, TX. She has been a Senior investigator at the Framingham Heart Study (FHS) for the past two decades and currently leads the Neurology and Neurogenetics cores. She has obtained over $60M in NIH funding over the past decade and is currently PI on multiple grants from the Alzheimer Association, the National Institutes on Aging (NIA) and the National Institute for Neurological Diseases and Stroke (NINDS). She has received Searle and Spivack awards for her neurological research.
She leads the Neurology Working Group within the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, the Cross Cohorts Consortium (CCC) and the Transomics for Precision Medicine (TOPMed) programs and is a PI on the International Genomics of Alzheimer Project (IGAP) and the Alzheimer Disease Sequencing Project (ADSP). Through these collaborations, she has advised several emerging efforts to study the genetics of dementia in Asia and amongst other non-European populations serving on the External Advisory Board for several international studies and funding organizations.
She also serves on the Editorial board for Stroke and Alzheimer’s and Dementia and has chaired the Neurology, Aging and Musculoskeletal Epidemiology study section of NIH, is currently a member of the Clinical Neurology and Neurodegeneration Study Section. She has over 350 peer-reviewed publications (H-index 107, i10 index 320) and has mentored 40 clinician scientists.
Her overarching interests are in identifying the biological and molecular pathways, both vascular and neurodegenerative that lead to clinical dementia, identifying genetic, blood-based, clinical and imaging early biomarkers that determine risk and parse disease heterogeneity, to develop, test and implement more effective, personalized (targeted) preventive and therapeutic interventions. She is committed to reducing disparities in access to dementia care, especially in South Texas.
Joe and Teresa Long School of Medicine at University of Texas Health Sciences Center